The streaming service described Rustin in a press release Tuesday as a man “who overcame an onslaught of obstacles, and altered the course of American history by organizing the 1963 March on Washington.”
He died in 1987 at the age of 75.
Rustin will also feature Chris Rock as Roy Wilkins, Glynn Turman as A. Philip Randolph and Audra McDonald as Ella Baker.
Wolfe and Domingo previously collaborated on the Netflix film, Ma Rainey’s Black Bottom.
Former President Barack and Michelle Obama’s Higher Ground company is is producing.